Test of accelerating collagen production at human corium fibroblast

Assess promoting effect of producing type I collagen at normal human corium fibroblast.
Collagen is one of the extracellular matrixes which relate to elasticity. Aging and photoaging decreases type I collagen at corium. Thus this leads to Wrinkles and sagging. Therefore, search for element which promotes synthesis of type I collagen is very important for developing an anti-wrinkle and anti-aging products.